PT-141 20mg
Bremelanotide — CNS-driven libido enhancement for men & women
Full Details & Dosage GuideClinical Uses
- Male erectile dysfunction (psychogenic and organic)
- Female hypoactive sexual desire disorder (HSDD)
- Sexual arousal and libido enhancement
- Central nervous system-mediated sexual dysfunction
Key Benefits
- Acts centrally — works regardless of cardiovascular status
- FDA-approved for HSDD in premenopausal women (Vyleesi)
- Elevates sexual desire, arousal, and satisfaction
- Effects last 6–12 hours with a single dose
- Effective in patients who don't respond to sildenafil/tadalafil
How It Works
PT-141 (Bremelanotide) is a cyclic heptapeptide that acts as a non-selective agonist at melanocortin receptors 1, 3, and 4 (MC1R, MC3R, MC4R). Unlike PDE5 inhibitors which work peripherally on vascular smooth muscle, PT-141 acts centrally in the hypothalamus and limbic system. MC4R activation is directly associated with sexual arousal circuits, producing desire and arousal at the neurological level.
Dosage Protocol
1–2 mg subcutaneous injection 45–60 minutes before sexual activity. Alternatively: 500 mcg–1 mg intranasal for a milder effect. Maximum 1 dose per 24 hours. Not for daily use — use as needed.
When to Expect Results
Onset: 45–60 minutes post-injection. Peak effect: 90–120 minutes. Duration: 6–12 hours. Nausea (common initial side effect) resolves with dose adjustment.
PT-141 10mg
Nasal PT-141 — convenient libido & arousal support
Full Details & Dosage GuideClinical Uses
- Male erectile dysfunction (psychogenic and organic)
- Female hypoactive sexual desire disorder (HSDD)
- Sexual arousal and libido enhancement
- Central nervous system-mediated sexual dysfunction
Key Benefits
- Acts centrally — works regardless of cardiovascular status
- FDA-approved for HSDD in premenopausal women (Vyleesi)
- Elevates sexual desire, arousal, and satisfaction
- Effects last 6–12 hours with a single dose
- Effective in patients who don't respond to sildenafil/tadalafil
How It Works
PT-141 (Bremelanotide) is a cyclic heptapeptide that acts as a non-selective agonist at melanocortin receptors MC1R, MC3R, and MC4R. It acts centrally in the hypothalamus and limbic system to produce desire and arousal at the neurological level, unlike PDE5 inhibitors which work peripherally.
Dosage Protocol
1–2 mg subcutaneous injection 45–60 minutes before sexual activity. Maximum 1 dose per 24 hours. Use as needed. 10mg vial provides multiple doses.
When to Expect Results
Onset: 45–60 minutes post-injection. Peak effect: 90–120 minutes. Duration: 6–12 hours.
PT-141 + Oxytocin Advanced 15mg + 600IU
Sexual enhancement + bonding hormone — the ultimate intimacy stack
Full Details & Dosage GuideClinical Uses
- Enhanced sexual desire with deep emotional bonding
- Couples intimacy optimization
- Female sexual dysfunction with relational component
- Male performance with enhanced emotional connection
- Psychogenic sexual dysfunction
Key Benefits
- PT-141 drives central arousal; oxytocin creates profound emotional connection
- Synergistic enhancement of both physical and psychological aspects of sexuality
- Oxytocin reduces performance anxiety
- Improved partner bonding and trust response
- Used in sex therapy and couples protocols
How It Works
PT-141 activates hypothalamic MC4R receptors to elevate sexual desire and arousal. Oxytocin acts on receptors in the amygdala, hypothalamus, and limbic system to reduce fear/anxiety and deepen emotional bonding. Together they create both drive and emotional-safety conditions for optimized sexual experience.
Dosage Protocol
PT-141: 1–2 mg subcutaneous injection + Oxytocin: 40–80 IU intranasal spray, both 45–60 minutes before intended activity. Single-use dosing as needed. Physician supervision required.
When to Expect Results
Onset: 45–60 minutes. Peak: 90–120 minutes. Duration: 6–10 hours. Oxytocin bonding effect from 10–15 min post-nasal administration.
Kisspeptin 10-Acetate 3mg
Master reproductive hormone — testosterone pulse & fertility support
Full Details & Dosage GuideClinical Uses
- Testosterone restoration (hypogonadotropic hypogonadism)
- LH/FSH pulsatility recovery after anabolic steroid use
- Fertility support in men and women
- Hypothalamic amenorrhea in women
Key Benefits
- Directly activates the hypothalamic GnRH pulse generator
- Restores natural LH and FSH pulsatility
- Supports testosterone recovery without suppressing the HPG axis
- Used in clinical fertility research globally
- No direct androgen activity — works upstream of the axis
How It Works
Kisspeptin 10-acetate is the biologically active C-terminal decapeptide of kisspeptin, the master regulator of the HPG axis. It activates the KISS1R/GPR54 receptor on hypothalamic GnRH neurons, driving pulsatile GnRH release that signals the pituitary to release LH and FSH, stimulating gonadal testosterone/estrogen production.
Dosage Protocol
10–20 mcg subcutaneous injection once daily or twice weekly. For testosterone recovery: 10–20 mcg daily for 4–8 weeks. Always under physician supervision with LH/FSH monitoring.
When to Expect Results
Days 3–7: measurable LH pulse amplitude increase. Weeks 2–4: testosterone levels begin rising. Weeks 4–8: normalization of HPG axis function. Fertility outcomes assessed at 12 weeks.
Kisspeptin 10mg
Large-volume Kisspeptin — extended hormonal optimization protocol
Full Details & Dosage GuideClinical Uses
- Moderate-to-severe hypogonadotropic hypogonadism
- Post-steroid testosterone restoration
- Male fertility with low LH/FSH
- Hypothalamic dysfunction
- GnRH pulse restoration
Key Benefits
- Higher-dose vial for extended or intensive protocols
- Suitable for patients with significant HPG axis suppression
- More flexibility in dosing across longer therapy windows
- Supports both testosterone and sperm production recovery
How It Works
Same mechanism as 3mg: activates KISS1R/GPR54 on hypothalamic neurons to stimulate pulsatile GnRH release, driving LH and FSH secretion and gonadal testosterone synthesis. The 10mg vial allows extended protocol duration or higher-frequency dosing for refractory cases.
Dosage Protocol
10–20 mcg subcutaneous injection per dose. 10mg vial covers 500–1,000 doses. Protocols: 4–12 weeks with serial LH, FSH, and testosterone labs every 4 weeks.
When to Expect Results
LH increase within 3–7 days, testosterone rise within 2–4 weeks, full HPG axis normalization at 8–12 weeks.
hCG 5,000 IU
Human Chorionic Gonadotropin — testosterone restoration & fertility
Full Details & Dosage GuideClinical Uses
- Testosterone restoration and testicular atrophy prevention
- Post-anabolic steroid cycle recovery (PCT)
- Male infertility treatment
- Hypogonadotropic hypogonadism
- Maintenance of testicular function during TRT
Key Benefits
- Directly mimics LH — stimulates Leydig cells to produce testosterone
- Prevents testicular atrophy during androgen suppression
- Maintains fertility potential during TRT
- Rapid testosterone restoration — effects within 24–72 hours
- FDA-approved for hypogonadism and fertility indications
How It Works
hCG shares identical beta subunit structure and receptor binding with Luteinizing Hormone (LH). It binds LH receptors on testicular Leydig cells, directly stimulating cAMP production and testosterone synthesis. Unlike upstream approaches (kisspeptin, clomiphene), hCG bypasses the hypothalamic-pituitary axis to act directly on the gonad.
Dosage Protocol
500–1,000 IU subcutaneous injection 2–3x per week. During TRT: 250–500 IU twice weekly. PCT: 500–1,000 IU every other day for 2–4 weeks. Reconstitute with sterile water. Store at 2–8°C after reconstitution.
When to Expect Results
Hours 24–48: measurable testosterone rise. Days 3–7: improvement in testicular volume. Weeks 2–4: full testosterone restoration. PCT: 4–8 weeks.
Oxytocin 40IU/puff
Bonding & trust hormone — mood, intimacy & social wellbeing
Full Details & Dosage GuideClinical Uses
- Social anxiety and bonding deficit
- Post-trauma trust restoration
- Male orgasm enhancement
- Partner intimacy and communication
- Autism spectrum disorder social facilitation
- Postpartum bonding support
Key Benefits
- Rapidly reduces social anxiety within 10–15 minutes
- Enhances feelings of trust, empathy, and emotional safety
- Intensifies orgasm and post-coital bonding
- Non-habit-forming with no withdrawal
- Well-studied in clinical populations
- Synergistic with PT-141 for sexual wellness
How It Works
Oxytocin is a 9-amino-acid neuropeptide synthesized in the hypothalamus. Administered intranasally, it binds receptors in the amygdala (reduces fear/threat response), hippocampus (trust and social memory), and reward pathways (enhances bonding). It also peripherally mediates smooth muscle contraction involved in orgasmic response.
Dosage Protocol
40 IU/puff intranasal spray: 1–3 puffs (40–120 IU) 10–20 minutes before desired effect. For sexual enhancement: use with PT-141. For social anxiety: 1 puff per nostril 15 minutes before social engagement. Use as needed.
When to Expect Results
Onset: 10–20 minutes. Peak: 30–60 minutes. Duration: 1–2 hours. Sexual effects synergistic with PT-141 from 45–60 minutes.
Enclomiphene 12.5mg
Selective estrogen modulator — natural testosterone stimulation
Full Details & Dosage GuideClinical Uses
- Secondary hypogonadism in men
- Testosterone restoration while preserving fertility
- Alternative to TRT for men wanting to maintain sperm production
- Estrogen-related gynecomastia reduction
- HPG axis normalization
Key Benefits
- Increases testosterone without suppressing LH/FSH
- Preserves testicular size and sperm production
- Oral convenience — no injections required
- Selective estrogen receptor modulator (SERM)
- Testosterone increases of 40–150% in clinical studies
How It Works
Enclomiphene is the trans-isomer of clomiphene citrate. It acts as a selective estrogen receptor antagonist (SERM) in the hypothalamus, blocking estrogen's negative feedback on GnRH pulsatility. This increases GnRH frequency, driving LH and FSH release and stimulating the testes to produce more testosterone — preserving the complete HPG axis and fertility.
Dosage Protocol
12.5 mg orally once daily in the morning. Starting dose — assess response at 4 weeks before considering escalation. Monitor testosterone, LH, FSH, and estradiol at 4 and 8 weeks. Typical protocol: 3–6 months.
When to Expect Results
Days 7–14: LH and FSH increase. Weeks 2–4: testosterone rising 40–100% above baseline. Weeks 4–8: full testosterone optimization. Weeks 8–16: sustained normalization.
Enclomiphene 25mg
High-dose Enclomiphene for hypogonadism & post-TRT recovery
Full Details & Dosage GuideClinical Uses
- Secondary hypogonadism in men
- Testosterone restoration while preserving fertility
- Alternative to TRT for men wanting to maintain sperm production
- HPG axis normalization post-steroid use
Key Benefits
- Higher maintenance dose for optimized testosterone response
- Preserves testicular size and sperm production
- Oral convenience — no injections required
- Selective estrogen receptor modulator (SERM)
- Testosterone increases of 40–150% in clinical studies
How It Works
Enclomiphene trans-isomer of clomiphene. Blocks hypothalamic estrogen receptors, removes negative feedback on GnRH pulsatility, drives LH/FSH release and testicular testosterone production without suppressing the HPG axis.
Dosage Protocol
25 mg orally once daily in the morning. Titrate up from 12.5 mg after 4-week assessment. Monitor testosterone, LH, FSH, estradiol at 4-week intervals. Protocol: 3–6 months.
When to Expect Results
Days 7–14: LH/FSH increase. Weeks 2–4: testosterone rising. Weeks 4–8: full optimization. Weeks 8–16: sustained normalization.
All peptides require UAE licensed physician review and mandatory blood work before dispensing. All protocols are subject to physician approval. Results vary by individual. These statements are for informational purposes only and do not constitute medical advice.